Nearly all National Institutes of Health grant applications should now be using updated application forms (FORMS-F; NOT-OD-20-026 and NOT-OD-20-077). However there are exceptions. See the NIH Extramural News: Don’t Forget to Use Updated Grant Application Forms (FORMS-F).
If you aren’t sure how to tell the form version you should using, check out Do I Have the Right Forms for My Application?